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| Functional Sugar alcohol as Prospective Food Materials | | PI ACADEMIC FORUM | |
|  | | | | | Date: June 30 (Wed) 11:45 ~ 12:15 Venue PI-2 | | | | | UNIVERSITY OF TOYAMA
DEPARTMENT OF HOSPITAL PHARMACY
ASSOCIATE PROFESSOR Mr. ATSUSHI KATO | | | | | I would like to introduce a functional sugar alcohol, which has a sweetness and good stability. This sugar alcohol showed the protective effects against the metabolic syndrome. |
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| Put a Mohs paste to practical use by to reform it to W/O emulsion. | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 11:45 ~ 12:15 Venue PI-1 | | | | | BED SORE ASSOCIATION
head office
chairman Mr. Tadakazu Kubo | | | | | Improve Mohs paste ,whichi include zinc chloride for surgery for skin cancer, with W/O emulsion in order to avoid side effect to surrounding skin. |
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| Asymmetric reduction of ketones with bifunctional chiral metal catalysts | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 12:30 ~ 13:00 Venue PI-1 | | | | | KANTO CHEMICAL CO INC
Central Research Laboratory, Technology & Development Division
Group Manager Mr. KUNIHIKO MURATA | | | | | Influence of hydrogen donor is examined in the asymmetric reduction of ketones with bifunctional chiral metal catalysts and effective preparative method of chiral alcohols is developed |
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| Oligolactates as novel functional foods for improving life-style relating diseases | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 12:30 ~ 13:00 Venue PI-2 | | | | | OSAKA OHTANI UNIVERSITY
School of Pharmacy, Department of Pharmaceutics
Professor Mr. Masahiro Murakami | | | | | The selective synthetic method of lactic acid oligomers (oligolactates) has been developed and their beneficial physiological functions against life-style relating diseases will be discussed. |
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| Stereocomplemetary preparation of a,b-unsaturated esters directed toward process chemistry | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 13:15 ~ 13:45 Venue PI-2 | | | | | KWANSEI GAKUIN UNIVERSITY
Department of Chemistry, School of Science and Technology
Professor Mr. Yoo TANABE | | | | | (E)-, (Z)-Stereocomplementary preparation of tri- or tetra-substituted a,b-unsaturated esters utilizing enol tosylation or phosphorylation of b-oxoesters and cross-coupling reactions |
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| Microbial production of sialic acid | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 13:15 ~ 13:45 Venue PI-1 | | | | | KYOWA HAKKO BIO CO., LTD.
BIOPROCESS DEVELOPMENT CENTER
DIRECTOR Mr. SATOSHI KOIZUMI | | | | | We report functions of sialic acid (N-acetylneuraminic acid) and its novel microbial production |
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| Production of functional polyphenols by enzymatic and chemical conversions | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 14:00 ~ 14:30 Venue PI-1 | | | | | NAGASAKI UNIVERSITY
Graduate School of Biomedical Sciences
Associate Professor Mr. Takashi Tanaka | | | | | Chemical and emzymatic methods to produce novel functional polyphenols will be introduced. |
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| A hydrolysis technology which used acidic saccharides and a functional evaluation . | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 14:00 ~ 14:30 Venue PI-2 | | | | | MEIJI UNIVERSITY
School of Science and Technology, Department of Applied Chemistry
Full-time Lecture Mr. Akihiko Murota | | | | | As a polysaccharide, fucoidan, alginic acid, etc. were used. In this lecture, report is performed from viewpoint of molecular weight activity correlation and structure activity relationship. |
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| Novel Trends in Catalytic Cross Coupling | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 14:45 ~ 15:15 Venue PI-1 | | | | | JOHNSON MATTHEY JAPAN INC.
Precious Metal Products Division
Technical Sales Mr. Kenichi Shimozawa | | | | | Novel trends in catalytic cross coupling will be discussed. |
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| New Bioactive Substances from Microorganisms -Inhibitors of MEP/Terpenoid Pathway and Water mold- | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 14:45 ~ 15:15 Venue PI-2 | | | | | RITSUMEIKAN UNIVERSITY
College of Pharmaceutical Sciences, Department of Pharmacy
Professor Mr. Nobutaka IMAMURA | | | | | In the course of screening for new bioactive substances from microorganisms, an enzyme (IspG) inhibitor of MEP/terpenoide biosynthetic pathway and a new selective anti-water mold compound were found. |
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| Synthesis and Structure-Activity Relationship of Pyripyropene A Derivatives as ACAT2 Inhibitors | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 15:30 ~ 16:00 Venue PI-2 | | | | | KITASATO UNIVERSITY
School of Pharmacy
Research Associate Mr. Masaki Ohtawa | | | | | We designed and synthesized new derivatives of pyripyropene A, the only potent inhibitor with a high isozyme selectivity toward ACAT2, for the development of new anti-atherosclerotic agents. |
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| Development of Transition Metal (Ru, Cu, Ag)-Catalyzed Atom Economical Reactions | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 15:30 ~ 16:00 Venue PI-1 | | | | | DOSHISHA UNIVERSITY
Faculty of Life and Medical Sciences
Research Associate Mr. OE Yohei | | | | | Transition metal-catalyzed addition reaction of heteroatom nucleophiles onto olefins, intramolecular cyclizations of olefinic nucleophiles, and asymmetric aldol type reactions will be shown. |
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| Particulate Design of Drugs by Rapid Expansion of Supercritical Carbon Dioxide Solutions Technique | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 16:15 ~ 16:45 Venue PI-1 | | | | | SHINSHU UNIVERSITY
Department of Chemistry and Material Engineering
Associate Professor Mr. Hirohisa Uchida | | | | | We have presented the study on the nanoparticles production and the particulate design strategy of several drugs using the rapid expansion of supercritical carbon dioxide solutions (RESS) technique. |
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| Combination of nanoparticle and physical activation for ping-point cell killing | | PI ACADEMIC FORUM | |
| | | | | | Date: June 30 (Wed) 16:15 ~ 16:45 Venue PI-2 | | | | | KOBE UNIVERSITY
Department of Chemical Science and Engineering
Associate Professor Mr. Chiaki Ogino | | | | | By combination of bio-molecular immobilized nano-particle and physical activation, the site specific cell killing could be performed. |
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| The efficient synthesis of chiral intermediates for the medicine | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 11:45 ~ 12:15 Venue PI-1 | | | | | TOKYO UNIVERSITY OF SCIENCE
Faculty of Engineering,Industrial Chemistry
Professor Mr. Yujiro HAYASHI | | | | | We have developed an efficient synthetic method for the synthesis of key chiral intermediates using organocatalysis. |
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| Anti-wrinkle activity of botanical extract | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 11:45 ~ 12:15 Venue PI-2 | | | | | NOF CORP.
Oleo & Speciality Chemicals Research Lab.
Senior Research Chemist Mr. Shinji Hayashi | | | | | Report on anti-wrinkle activity of botanical extract for potential cosmetic ingredient |
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| The effectiveness on new influenza and various causative bacteria by Mt. Fuji lava powder. | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 12:30 ~ 13:00 Venue PI-1 | | | | | TAMAGAWA UNIVERSITY
Faculty of Engineering
Research student (Former Professor TAMAGAWA UNIVERSITY) Mr. Mitsuo Terasawa | | | | | The Mt. Fuji lava powder showed the effectiveness of inactivation on the new influenza. In addition, various causative bacteria possessed anti-bacterium revitalization. |
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| Study and Development of Photo-oxidation with Molecular Oxygen | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 12:30 ~ 13:00 Venue PI-2 | | | | | GIFU PHARMACEUTICAL UNIVERSITY
Labolatory of Pharmaceutical Synthetic Chemistry Faculty of Pharnaceutical Science
Professor Mr. Akichika Itoh | | | | | We have found that alcohols and methyl group at aromatic nucleus were oxidized directly to the corresponding carboxylic acids in an oxygen atmosphere under irradiation of UV or VIS. |
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| Development of drugs for skin disorders using the amphiphilic agent complexes | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 13:15 ~ 13:45 Venue PI-1 | | | | | NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES
Faculty of Pharmaceutical Sciences
Associate Professor Ms. Nahoko IIMURA | | | | | We have developed drugs for skin disorders using the technique of complex formation with amphiphilic agent and examined about their skin permeation |
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| Development of alpha-Glucosidase Inhibitors (AGIs) as Remedies for Diabetics in Early Stage | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 14:00 ~ 14:30 Venue PI-1 | | | | | KINKI UNIVERSITY
School of Pharmacy
professor Mr. Osamu Muraoka | | | | | New potent AGIs as remedies for diabetics were developed through SAR studies on salacinol, a novel natural AGI isolated from Ayurvedic traditional medicine Salacia reticulata, as a seed compound. |
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| Design, synthesis of novel biphenylcarboxylic acid type PPAR delta antagonists | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 14:45 ~ 15:15 Venue PI-2 | | | | | OKAYAYA UNIVERSITY
Graduate School of Medicine, Dentistry and Pharmaceutical Sciencs, Okayama University
professor Mr. Hiroyuki Miyachi | | | | | We designed and synthesized novel PPAR delta-selective antagonists based on the crystal structure of the PPAR delta full agonist TIPP-204 bound to the PPAR delta ligand binding domain. |
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| Steroid Labeled Compounds | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 14:45 ~ 15:15 Venue PI-1 | | | | | WASEDA UNIVERSITY
Faculty of Science and Engineering
Professor Mr. Isao Shimizu | | | | | A stable carbon isotope labeled estradiol and a labeled fluorescent estradiol are introduced. In addition to the estradiol, we can provide other labeled small molecular biologically active compounds. |
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| Discovery of HDAC8-selective inhibitors that show anti-T cell lymphoma activity | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 15:30 ~ 16:00 Venue PI-1 | | | | | NAGOYA CITY UNIVERSITY
Graduate School of Pharmaceutical Sciences / Department of Organic and Medicinal Chemistry
Lecturer Mr. Takayoshi Suzuki | | | | | We identified HDAC8-selective inhibitors by a screening of an HDAC inhibitor library. These inhibitors showed anti-T cell lymphoma activity. |
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| Facile preparation of highly-stable PEG-PLA nanoparticles containning hydrophobic drugs | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 15:30 ~ 16:00 Venue PI-2 | | | | | OKAYAMA UNIVERSITY
Graduate school of Environmental Science
Associate Professor Mr. TSUTOMU ONO | | | | | We have developed highly-stable PEG-PLA nanoparticles with the complete inclusion of hydrophobic compounds. This is a great potential for an intravenous drug carrier. |
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| A Convenient and Convergent Synthesis of α,α-Difluoroketones through Selective C-F Bond Cleavage | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 16:15 ~ 16:45 Venue PI-2 | | | | | TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES
SCHOOL OF PHARMACY
Assistant Professor Mr. HIkaru Yanai | | | | | α,α-Difluoroketone functionality was easily constructed by regio-specific defluorinative alkylation reaction of trifluoroacetaldehyde N,O-acetals. |
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| Structural Homology Analysis of Chiral Pharmaceutical Compounds Using Conformational Code | | PI ACADEMIC FORUM | |
| | | | | | Date: July 1 (Thur) 16:15 ~ 16:45 Venue PI-1 | | | | | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (AIST)
Institute for Environmental Management Technology
Research Scientist Mr. Hiroshi Izumi | | | | | VCD analysis of chiral pharmaceuticals for configuration determination and structural homology analysis of antibodies using conformational code for detection of irreversible change are presented. |
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| Cellulose and contractile fibers in the tunic of Halocynthia roretzi | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 11:45 ~ 12:15 Venue PI-1 | | | | | FACULTY OF ENGINEERING, TOHOKU GAKUIN UNIVERSITY
Faculty of Engineering, Tohoku Gakuin University
Associate Professor Ms. Yoko Kato | | | | | Cellulose is notable in tissue engineering. The tunic of Halocynthia roretzi indicates that cellulose can coexist with multiple kinds of contractile fibers. |
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| Evaluation method for research of whitening agent, hair restorer and anti-photo aging agent in vitro | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 11:45 ~ 12:15 Venue PI-2 | | | | | TOKYO UNIVERSITY OF TECHNOLOGY
School of Bioscience and Biotechnology
Professor Mr. Kazuhisa Maeda | | | | | My presentation is about the in vitro evaluation method for finding out the material which is whitening, a hair restorer, and an anti-photo aging from plant extracts. |
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| Charactrization of marine collagen, marine collagen hydrolysate, and feathar keratin hydrolysate | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 12:30 ~ 13:00 Venue PI-2 | | | | | TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
Agriculture
Associate Professor Mr. Yoshihiro Nomura | | | | | Explanation of marine collagen, marine collagen hydrolysate and feather keratin hydrolysate for cosmetic use. |
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| Nucleophilic Fluorination of Catechols and New Fluorine Derivatives for PET Imaging | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 12:30 ~ 13:00 Venue PI-1 | | | | | UNIVERSITY OF SHIZUOKA
School of Pharmaceutical Sciences
Professor Mr. Shuji Akai | | | | | “Nucleophilic substitution of a hydroxyl group of various catechols with fluorine” and “Preparation of a long-chain [18F]F-PEG and its pharmacokinetic analysis by PET imaging” will be presented. |
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| Natural killer activity enhancing agent and its application | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 14:00 ~ 14:30 Venue PI-1 | | | | | TOKYO INSTITUTE OF TECHNOLOGY
Division of Process Systems Engineering, Chemical Resources Laboratory
assistant professor Mr. Hiroyuki Tanaka | | | | | A method is shown to provide an agent to promote natural killer activity for effective immunotherapy. |
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| Synthesis and bioactivity evaluation of polyphenols such as catechins and flavonoids | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 14:00 ~ 14:30 Venue PI-2 | | | | | UNIVERSITY OF SHIZUOKA
Department of Synthetic Organic and Medicinal Chemistry
Proffessor Mr. Toshiyuki Kan | | | | | Novel synthetic method for polyphenols and SAR results of the synthetic compounds would be discussed. |
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| Functions of the "Polymer Surfactants Derived from Chitosan" and application of the micro-capsule | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 14:45 ~ 15:15 Venue PI-2 | | | | | RESEACH INSTITUTE FOR NOVEL NATURAL-MATERIALS CO., LTD.
Head Office
Senior Managing Director Mr. Yasuo Sakai | | | | | Chitosan shows various pharmacological effects such as antibacterial activities etc.. Introduction of polymer surfactants derived from chitosan and the report on functions and saftys |
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| Effective synthetic methods for organofluorine compounds: introduction of a CF3 or CF2 group | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 14:45 ~ 15:15 Venue PI-1 | | | | | SETSUNAN UNIVERSITY
Laboratory of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences
Research Associate Mr. Kazuyuki Sato | | | | | Many medicines have one or some fluorine substituent(s) that strongly improve the bio and pharmacological activities. We’ll show some effective methods for introducing fluoroalkyl groups such as CF3. |
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| Design and synthesis of powerful vitamin D derivatives | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 15:30 ~ 16:00 Venue PI-2 | | | | | TEIKYO UNIVERSITY
Faculty of Pharmaceutical Sciences
Professor Mr. ATSUSHI KITTAKA | | | | | Active vitamin D3 analogs were synthesized, and their biological activity was evaluated as potential therapeutic agents. |
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| Carbon Electrode Surface Design for Development of Disposable High Sensitive Biosensors | | PI ACADEMIC FORUM | |
| | | | | | Date: July 2 (Fri) 15:30 ~ 16:00 Venue PI-1 | | | | | KUMAMOTO UNIVERSITY
Graduate School of Science and Technology
Assistant Professor Mr. Masato Tominaga | | | | | To develop high sensitive biosensors, the surface structure design of carbon nanotubes was investigated. |
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